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蟾毒靈
分析標(biāo)準(zhǔn)品,HPLC≥98%
Bufalin
CAS號：465-21-4
分子式： C24H34O4
分子量：386.53
MDL：MFCD00056525
貨號 | 規(guī)格/參數(shù)/品牌 | 價格 | 貨期 |
YJ-B20152-5mg | 分析標(biāo)準(zhǔn)品,HPLC≥98% | ￥600.00 | 現(xiàn)貨 |
YJ-B20152-20mg | 分析標(biāo)準(zhǔn)品,HPLC≥98% | ￥1020.00 | 現(xiàn)貨 |
YJ-B20152-100mg | 分析標(biāo)準(zhǔn)品,HPLC≥98% | ￥2980.00 | 現(xiàn)貨 |
產(chǎn)品介紹
熔點：242-243℃
沸點：556.6 ℃ at 760 mmHg
比旋光度：D -20°
外觀：針狀晶體
溶解性：DMSO : 100 mg/mL (258.72 mM; Need ultrasonic)
儲存條件：2-8℃
注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。
參考文獻(xiàn)(33篇)
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21. [IF=2.193] Zhang Mei-Tuo et al."Strategic Combination of Isocratic and Gradient Elution for Simultaneous Separation of Polar Compounds in Traditional Chinese Medicines by HPLC."J Anal Methods Chem. 2018;2018:7569283
20. [IF=2.311] Jinlin Xie et al."Bufalin suppresses the proliferation and metastasis of renal cell carcinoma by inhibiting the PI3K/Akt/mTOR signaling pathway."Oncol Lett. 2018 Sep;16(3):3867-3873
19. [IF=2.748] Tao Song et al."Bufalin, a bufanolide steroid from the parotoid glands of the Chinese toad, suppresses hERG K+ currents expressed in HEK293 cells."Fund Clin Pharmacol. 2017 Dec;31(6):695-700
18. [IF=2.748] Tao Song et al."Bufalin, a bufanolide steroid from the parotoid glands of the Chinese toad, inhibits L-type Ca2+ channels and contractility in rat ventricular myocytes."Fund Clin Pharmacol. 2017 Jun;31(3):340-346
17. [IF=3.743] Yu-Long Lan et al."Bufalin inhibits glioblastoma growth by promoting proteasomal degradation of the Na+/K+-ATPase α1 subunit."Biomed Pharmacother. 2018 Jul;103:204
16. [IF=4.101] Yao Liu et al."Effects of bufalin on the mTOR/p70S6K pathway and apoptosis in esophageal squamous cell carcinoma in nude mice."Int J Mol Med. 2017 Aug;40(2):357-366
15. [IF=6.284] Lan Yu-Long et al."The sodium pump α1 subunit regulates bufalin sensitivity of human glioblastoma cells through the p53 signaling pathway."Cell Biol Toxicol. 2019 Dec;35(6):521-539
14. Haiyan Hu, Qi Qi, Ziyi Dong, Xianglong Yu, Yujia Mo, Juyuan Luo, Yan Wang, Shouying Du, Yang Lu,
Albumin coated trimethyl chitosan-based targeting delivery platform for photothermal/chemo-synergistic cancer therapy,
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2020,
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12. Song, Tao, et al. "Bufalin, a bufanolide steroid from the parotoid glands of the Chinese toad, inhibits L‐type Ca2+ channels and contractility in rat ventricular myocytes." Fundamental & clinical pharmacology 31.3 (2017): 340-346.https:##doi.org/10.1111/fc
11. Song, Tao, et al. "Bufalin, a bufanolide steroid from the parotoid glands of the Chinese toad, suppresses hERG K+ currents expressed in HEK 293 cells." Fundamental & clinical pharmacology 31.6 (2017): 695-700.https:##doi.org/10.1111/fcp.12306
10. Liu, Yao, et al. "Effects of bufalin on the mTOR/p70S6K pathway and apoptosis in esophageal squamous cell carcinoma in nude mice." International journal of molecular medicine 40.2 (2017): 357-366. https:##doi.org/10.3892/ijmm.2017.3039
9. Liu, Yao, et al. "Effects of bufalin on the mTOR/p70S6K pathway and apoptosis in esophageal squamous cell carcinoma in nude mice." International journal of molecular medicine 40.2 (2017): 357-366. https:##doi.org/10.3892/ijmm.2017.3039
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4. 丁妍,王小玲,鄧會巖,蘇麗宏,張培,劉月平.蟾蜍靈抑制Raf/MEK/細(xì)胞外信號調(diào)節(jié)激酶信號通路活化影響人食管鱗癌細(xì)胞增殖及遷移機(jī)制研究[J].中國全科醫(yī)學(xué),2015,18(21):2535-2541.
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1. 丁妍 王小玲 柳慧 等. Bufalin促進(jìn)人食管癌細(xì)胞ECA109凋亡的研究[J]. 食管外科電子雜志 2014(02):49-54.
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